Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8949958 | Pathology - Research and Practice | 2018 | 7 Pages |
Abstract
Based on our results, the miR-498 can effectively suppress TIM-3 expression in the AML cell line. TIM-3 suppression, in turn, inhibits malignant cell proliferation and induces its apoptosis. Collectively, suppression of TIM-3 by miR-498 can be considered as a potential powerful way for treatment of AML.
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Authors
Yaser Moghaddam, Alireza Andalib, Maryam Mohammad-Ganji, Vida Homayouni, Mohammadreza Sharifi, Mazdak Ganjalikhani-Hakemi,