| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8950917 | Bone | 2018 | 62 Pages |
Abstract
We provided some mechanisms of action for osteocalcin in the amelioration of insulin resistance in obesity: in WAT, osteocalcin improves insulin resistance by decreasing inflammation, and increasing insulin signaling and the expression of Slc2a4/GLUT4; and, in bone, osteocalcin increases the secretion of uncarboxylated osteocalcin by improving insulin resistance.
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Authors
J.A.C. Guedes, J.V. Esteves, M.R. Morais, T.M. Zorn, D.T. Furuya,