| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8950925 | Diabetes Research and Clinical Practice | 2018 | 29 Pages |
Abstract
This study is the first to demonstrate a trend for increased Sestrin2 level in subjects with metabolic syndrome. In particular, in subjects with type 2 diabetes, Sestrin2 was significantly related to insulin resistance and percentage body fat, suggesting its potential as a novel modulatory factor for metabolic disorders in humans.
Keywords
AMPKESHHDLALTDBPHOMA-IRDSCFCIMTDXAFPGHbA1chsCRPEuropean Society of HypertensionbaPWVhigh-density lipoproteinASTAspartate aminotransferaseAlanine aminotransferaseHomeostatic model assessment of insulin resistanceEuropean Society of Cardiologycardiovascular diseaseanalysis of varianceANOVAEnzyme-linked immunosorbent assayELISAdual-energy X-ray absorptiometryESCBUNCVDBrachial-ankle pulse wave velocitybody mass indexBMIendoplasmic reticulumCarotid intima-media thicknessCoefficient of Variationdiastolic blood pressureFasting plasma glucoseblood urea nitrogenHemoglobin A1chigh-sensitivity C-reactive proteinAMP-dependent protein kinase
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Authors
Hye Soo Chung, Hwan-Jin Hwang, Soon Young Hwang, Nam Hoon Kim, Ji A. Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi, Hye Jin Yoo,