Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8952658 | Journal of Pediatric Surgery | 2018 | 6 Pages |
Abstract
Rat gonocyte transformation is normal in both normally descending and future UDT. This suggests that congenitally cryptorchid rats may not develop testicular cancer because gonocytes (the putative origin of malignant degeneration) normally transform into spermatogonial stem cells before UDT occurs and the risk of thermal injury develops. This suggests the TS rat may be a good model for acquired UDT in human where the abnormal testicular position develops after gonocyte transformation is completed in the first year.
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Authors
Moshe Loebenstein, John Hutson, Ruili Li,