| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8956099 | CMGH Cellular and Molecular Gastroenterology and Hepatology | 2018 | 16 Pages |
Abstract
After esophagojejunostomy in rats, metaplastic columnar-lined esophagus develops via a wound healing process that does not appear to involve cellular reprogramming of progenitor cells. This process involves EMT-associated migration of jejunal cells into the esophagus, where they likely have a competitive advantage over squamous cells in the setting of ongoing gastroesophageal reflux disease.
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Authors
Agoston T. Agoston, Thai H. Pham, Robert D. Odze, David H. Wang, Kiron M. Das, Stuart J. Spechler, Rhonda F. Souza,