Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8956131 | EBioMedicine | 2018 | 5 Pages |
Abstract
These results suggest that estrogen plays an important role in RCC etiology and may modify the association between obesity and RCC risk in women. We hypothesize that estrogen may up-regulate IGF-1R and potentiate the deleterious effects of obesity-related elevations of insulin and IGFs.
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Authors
Lijiang Sun, Fan Chao, Bo Luo, Dingwei Ye, Jun Zhao, Qiang Zhang, Xiaocheng Ma, Guiming Zhang,