| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8956332 | Molecular and Cellular Endocrinology | 2018 | 10 Pages |
Abstract
Hepatic succinate accumulation served as a metabolic signal to promote liver fibrosis through HIF-1α induction. Curcumin reduced succinate accumulation by combating fatty acid oxidation and prevented HSCs activation by blocking succinate/HIF-1α signaling pathway.
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Authors
Linlin She, Dan Xu, Zixia Wang, Yirui Zhang, Qingli Wei, Jiye Aa, Guangji Wang, Baolin Liu, Yuan Xie,