Article ID Journal Published Year Pages File Type
8956564 Progress in Neuro-Psychopharmacology and Biological Psychiatry 2019 20 Pages PDF
Abstract
This study provided confirmatory and new findings. SH3GL2 (endophilin A1) showed a role in suicidal ideation that may be due to its relevance to the glutamate system. SHC4 regulates BDNF-induced MAPK activation and was previously associated with depression. CLVS1 is involved in lysosome maturation and was for the first time associated with a psychiatric trait. GO:0048661 may mediate the risk of substance disorder through an effect on neurodevelopment/neuroplasticity.
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Life Sciences Neuroscience Biological Psychiatry
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