Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8957692 | Gastroenterology | 2018 | 13 Pages |
Abstract
In a multicenter randomized trial of patients with PSC and a dominant stricture, short-term stents were not superior to balloon dilatation and were associated with a significantly higher occurrence of treatment-related SAEs. Balloon dilatation should be the initial treatment of choice for dominant strictures in patients with PSC. This may be particularly relevant to patients with an intact papilla. ClinicalTrials.gov no. NCT01398917.
Keywords
MRCPSF36ULNUDCASAEASGEACCSDSMBPEPPSCERCPEndoscopic retrograde cholangiopancreatographyASTAspartate aminotransferaseALPAlkaline phosphataseAmerican Society for Gastrointestinal EndoscopyUrsodeoxycholic acidUpper limit of normalRight upper quadrant painDrainagebiliarySurgerySerious adverse eventconfidence intervalData Safety Monitoring Boardpost–endoscopic retrograde cholangiopancreatography pancreatitisPrimary sclerosing cholangitis
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Authors
Cyriel Y. Ponsioen, Urban Arnelo, Annika Bergquist, Erik A. Rauws, Vemund Paulsen, Paolo Cantú, Ilaria Parzanese, Elisabeth M. De Vries, Kim N. van Munster, Karouk Said, Olivier Chazouillères, Benoit Desaint, Astrid Kemgang, Martti Färkkilä,