| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8961188 | Journal of Proteomics | 2018 | 20 Pages |
Abstract
UVB and UVC radiations compel metastatic-melanoma cells carrying the BRAFV600D oncogenic mutation to undergo apoptosis, necroptosis and increased autophagy, while synergism with Irinotecan reinforces UV-radiation's anti-tumorigenic activity. UV radiation-induced melanoma-cell escapers acquire low levels of autophagy, enhanced EMT program and Cisplatin resistance, therefore unveiling UV-radiation's tumorigenic activity.171
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Authors
Eumorphia G. Konstantakou, Athanassios D. Velentzas, Athanasios K. Anagnostopoulos, Aikaterini F. Giannopoulou, Ema Anastasiadou, Issidora S. Papassideri, Gerassimos E. Voutsinas, George Th. Tsangaris, Dimitrios J. Stravopodis,