Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8961189 | Journal of Proteomics | 2018 | 49 Pages |
Abstract
This study integrates transcriptome/translatome and proteome/secretome to analyze gene expression changes in human colon cancer cells under hypoxic conditions. Candidate proteins/genes in this integrated omics analysis were further validated by immunoblotting, quantitative real-time RT-PCR, and polysome profiling. The datasets would be useful to uncover the molecular mechanisms of hypoxia-induced gene regulation in colorectal cancer.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jeng-Ting Chen, Chien-Chun Liu, Jau-Song Yu, Hung-Hsuan Li, Ming-Chih Lai,