Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8962206 | Radiotherapy and Oncology | 2018 | 7 Pages |
Abstract
In this report the radiobiological consequences of target volume transformation caused by modern imaging of the neck are evaluated, and theoretically derived reductions of dose in radiotherapy for head and neck cancer are proposed. The concept of target volume transformation and subsequent strategies for dose adaptation applies to many other tumor types as well. Awareness of this concept may result in new strategies for target definition and selection of dose levels with the aim to provide optimal tumor control with less toxicity.
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Authors
Sven van den Bosch, Wouter V. Vogel, Cornelis P. Raaijmakers, Tim Dijkema, Chris H.J. Terhaard, Abrahim Al-Mamgani, Johannes H.A.M. Kaanders,