Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8962217 | Radiotherapy and Oncology | 2018 | 7 Pages |
Abstract
Advanced ypT-stage, lymphatic invasion and RTD â¥10â¯mm were prognostic factors for LNM in patients ypT0-2 rectal carcinoma treated with CRT and surgery within both phase 3 trials. The high incidence of LNM in the ypT1-2 group needs to be taken into consideration in the context of oncological safety and indicate that LE should be advocated with great caution in this patient subgroup. The prognostic pathological factor identified here could help guide decision of LE vs TME after standard CRT.
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Authors
Jens Müller von den Grün, Arndt Hartmann, Rainer Fietkau, Michael Ghadimi, Torsten Liersch, Werner Hohenberger, Jürgen Weitz, Rolf Sauer, Christian Wittekind, Philipp Ströbel, Claus Rödel, Emmanouil Fokas,