| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8963697 | Journal of Allergy and Clinical Immunology | 2018 | 39 Pages |
Abstract
These data demonstrate the potential application of T-cell gene therapy in reconstituting cytotoxic function and protection against HLH in the setting of perforin deficiency.
Keywords
PRF1GFPFHLHLHeffector memory TTCMHSCTIRESLCMVnatural killerTeminternal ribosomal entry siteT cellsHemophagocytic lymphohistiocytosisfamilial hemophagocytic lymphohistiocytosiswild-typeLymphocytic choriomeningitis virusgreen fluorescent proteinpenicillin and streptomycinHematopoietic stem cell transplantationGene therapy
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Authors
Sujal MD, Marlene PhD, Miguel PhD, Ida PhD, Juan Carlos MD, Michael P. PhD, Axel MD, PhD, Philip G. PhD, Claire MBBS, PhD, Stephan MD, PhD, Kai MD, PhD, Adrian J. MBBS, PhD, H. Bobby MBBS, PhD,