Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8964725 | The Spine Journal | 2018 | 26 Pages |
Abstract
There is significant variability in the expression of cytokines throughout the fusion process after treatment with rhBMP-2. The inflammatory response appears to peak early (1 and 6 hours), followed by a significant decrease with rhBMP-2 treatment. However, the growth factor expression appears to be suppressed early (1 and 6 hours), followed by a peak at 24 hours, and a second peak at Day 7.
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Authors
John D. MD, Dessislava Z. PhD, Greg D. MD, Brian P. BA, Anuj BS, Corbin W. BS, Alexander R. MD, PhD, MBA, D. Greg MD, Christopher K. MD, MBA,