Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8969886 | Vaccine | 2005 | 10 Pages |
Abstract
Using a stochastic simulation model of influenza transmission, clinical illness, and economic costs, we estimated the population-wide benefits of routinely vaccinating US children (ages 6 months to 18 years) against influenza. Disease burden was projected to decline as a result of both reduced susceptibility to infection among vaccinees and reductions in disease transmission to others in the community. Vaccination of 20% of children would reduce the total number of influenza cases in the US by 46%; 80% coverage would reduce the total number of cases by 91%. Similar reductions were estimated to occur in influenza-related mortality and economic costs.
Keywords
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Immunology
Authors
Derek Weycker, John Edelsberg, M. Elizabeth Halloran, Ira M. Jr., Azhar Nizam, Vincent Ciuryla, Gerry Oster,