| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8996463 | Medical Hypotheses | 2005 | 7 Pages |
Abstract
We postulate that the molecular link between defective GALT enzyme, which result in classic galactosemia; and the cerebroside galactosyl transferase, which is responsible for galactosylation of cerebrosides is dependent on the cellular concentrations of UDP-galactose. We further hypothesize that a threshold concentration of UDP-galactose exist below which the integrity of cerebroside galactosylation suffers.
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Authors
Phiyani Justice Lebea, Pieter J. Pretorius,