Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8998328 | Neuropharmacology | 2005 | 13 Pages |
Abstract
We were thus able to pharmacologically isolate the mGluR2-mediated function in the rat GP using an mGluR2-specific allosteric modulator. Therefore, our findings do not only shed light on the functions of group II mGluRs in the GP, they also illustrate the therapeutic potential of mGluR-targeting allosteric modulators in neurological disorders such as Parkinson's disease.
Keywords
Related Topics
Life Sciences
Neuroscience
Behavioral Neuroscience
Authors
Olga Poisik, Dinesh V. Raju, Marc Verreault, Alice Rodriguez, Oluseyi A. Abeniyi, P. Jeffrey Conn, Yoland Smith,