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Kynurenine 3-mono-oxygenase inhibitors reduce glutamate concentration in the extracellular spaces of the basal ganglia but not in those of the cortex or hippocampus

Article ID Journal Published Year Pages File Type
8998502 Neuropharmacology 2005 8 Pages PDF
Abstract
Our data show that KMO inhibitors increase brain KYNA synthesis and selectively reduce GLU extracellular concentration in the basal ganglia.
Keywords
NMDAKynurenine hydroxylaseNicotinic ACh receptorsbasal gangliamicrodialysiskynurenine
Related Topics
Life Sciences Neuroscience Behavioral Neuroscience
Preview
Kynurenine 3-mono-oxygenase inhibitors reduce glutamate concentration in the extracellular spaces of the basal ganglia but not in those of the cortex or hippocampus
Authors
F. Moroni, A. Cozzi, R. Carpendo, G. Cipriani, O. Veneroni, E. Izzo,
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Journal
Neuropharmacology
Journal: Neuropharmacology
Related Categories
NMDA
Kynurenine hydroxylase
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microdialysis
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