Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8999785 | Phytomedicine | 2005 | 4 Pages |
Abstract
Ten xanthones with one or two isoprenoid groups and a prenylated benzophenone isolated from roots of Cudrania cochinchinensis (Moraceae) were tested for their antimicrobial activities against vancomycin-resistant enterococci (VRE). Among these compounds, gerontoxanthone H exhibited considerable antibacterial activity against five VRE strains (VanA, VanB and VanC) (MICs=1.56μg/ml). Four xanthones, 1,3,7-trihydroxy-2-prenylxanthone, gerontoxanthone I, alvaxanthone and isoalvaxanthone, showed weaker antibacterial activity against these VREs (MICs=3.13-6.25 μg/ml).
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Authors
T. Fukai, Y. Oku, A.-J. Hou, M. Yonekawa, S. Terada,