| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9005573 | Clinical Therapeutics | 2005 | 11 Pages |
Abstract
Understanding the PK profile and formulations of bupropion can help optimize clinical use. Bupropion is metabolized extensively, resulting in 3 active metabolites. This metabolic profile, various patient factors (eg, age, medical illnesses), and potential drug interactions should be considered when prescribing bupropion. The 3 formulations-bupropion, bupropion SR, and bupropion XL-are bioequivalent and offer options to optimize treatment for patients with MDD.
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Authors
MD Jefferson, MSc, MD Pradko, PhD Muir,