Effects of antioxidant supplementation on postprandial oxidative stress and endothelial dysfunction: A single-blind, 15-day clinical trial in patients with untreated type 2 diabetes, subjects with impaired glucose tolerance, and healthy controls

Article ID	Journal	Published Year	Pages	File Type
9005578	Clinical Therapeutics	2005	10 Pages	PDF

Abstract

This study showed changes in oxidation-reductionbalance, NO bioavailability, and nonthrombogenic endothelial factors after a moderate-fat meal in patients with type 2 diabetes and those with IGT, but these postprandial changes were reverse in all subjects after 15 days of standard antioxidant supplementation. These findings suggest that the use of anti-oxidants may have decreased oxidative stress in these subjects.

Keywords

Endothelial damage Antioxidants impaired glucose tolerance Diabetes Oxidative stress Reactive oxygen species

Related Topics

Health Sciences Medicine and Dentistry Medicine and Dentistry (General)

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Effects of antioxidant supplementation on postprandial oxidative stress and endothelial dysfunction: A single-blind, 15-day clinical trial in patients with untreated type 2 diabetes, subjects with impaired glucose tolerance, and healthy controls

Authors

MD Neri, MD Signorelli, ED Torrisi, MD Pulvirenti, MD Mauceri, MD Abate, MD Ignaccolo, MD Bordonaro, MD Cilio, MD Calvagno, MD Leotta,