Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9006265 | Current Opinion in Pharmacology | 2005 | 7 Pages |
Abstract
Androgens increase bone mass in specific skeletal compartments through effects on bone cells, enhancing osteoblast activity but inhibiting that of osteoclasts. The mechanism of action of androgens might involve both classic androgen receptor transcriptional activation and rapid non-genomic effects, and could also be dependent upon low levels of estrogen.
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Authors
Kristine M Wiren,