| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9006270 | Current Opinion in Pharmacology | 2005 | 7 Pages |
Abstract
Adipose tissue secretes a variety of factors in a manner dependent upon its metabolic state. These factors are derived from adipocyte or non-adipocyte fractions, and include proteins, metabolites and hormones. Obesity is a major risk factor for type 2 diabetes and cardiovascular disease, and adipocyte-derived factors might contribute to or ameliorate obesity-associated pathologies such as insulin resistance, dyslipidemia, vascular dysfunction and a chronic inflammatory and prothrombotic state.
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Authors
Ruth E Gimeno, Lori D Klaman,