Genetic Correlates of Maladaptive Beliefs: COMT VAL158MET and Irrational Cognitions Linked Depending on Distress

These results were significant for overall irrational beliefs and its subtypes, but not for rational beliefs, the functional counterpart of irrationality. In light of the study's limitations, the results should be considered as preliminary. If replicable, these findings have potential implications for therapygenetics, changing the view that COMT Val158Met might be of greater relevance when treatment modality does not rely on cognitive variables.