Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9012983 | Life Sciences | 2005 | 13 Pages |
Abstract
Neural stem cells cultured as neurospheres were used to assess the effects of P. notoginseng on the production of neurons and glia. The crude saponins (PNS) and ginsenoside-Rd promote the differentiation of neurospheres into astrocytes. Ginsenoside-Rd increases the production of astrocytes in a dose-dependent manner. On the other hand, both PNS and ginsenoside-Rd induce a weak but significant effect by decreasing the number of neurons. The other ginsenosides do not induce any differentiation on both neurons and astrocytes.
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Authors
Qin Shi, Qi Hao, Julien Bouissac, Yang Lu, Songjiu Tian, Bang Luu,