| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9016467 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2005 | 7 Pages |
Abstract
A significant decrease in 5-HT1A receptor density in DRN, MRN, and hippocampus, accompanied by an increase in labeling of 5-HT1A receptor in thalamus, hypothalamus, and amygdala was observed in ST animals. FS induced a decrease in the 5-HT concentration in the thalamus-hypothalamus, accompanied by an increase in hippocampus areas without affecting 5-HT concentration in the brainstem. Additionally, 5-HIAA/5-HT ratio in the thalamus-hypothalamus area was increased. This study showed that stress alters both 5-HT concentration and 5-HT1A receptors in a region-specific manner.
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Authors
Alfredo Briones-Aranda, Luisa Rocha, Ofir Picazo,