Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9017357 | Pulmonary Pharmacology & Therapeutics | 2005 | 6 Pages |
Abstract
These results suggest that the XO activity is increased in COPD airways, possibly due to its gene upregulation by proinflammatory cytokines. Because the XO activity was significantly correlated with the degree of airway obstruction, these cytokine-XO production pathways may play a key role in the inflammation of COPD.
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Authors
Yuichi Komaki, Hisatoshi Sugiura, Akira Koarai, Masafumi Tomaki, Hiromasa Ogawa, Takefumi Akita, Toshio Hattori, Masakazu Ichinose,