Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9018322 | Toxicology and Applied Pharmacology | 2005 | 6 Pages |
Abstract
The dopamine transporter (DAT) is a plasma membrane transport protein expressed exclusively within a small subset of CNS neurons. It plays a crucial role in controlling dopamine-mediated neurotransmission and a number of associated behaviors. This review focuses on recent data elucidating the role of the dopamine transporter in neurotoxicity and a number of CNS disorders, including Parkinson disease, drug abuse, and attention deficit hyperactivity disorder (ADHD).
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Michael J. Bannon,