| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9021474 | International Congress Series | 2005 | 4 Pages |
Abstract
The effects of a clinically relevant concentration (1.5%, 1 rat minimum alveolar concentration) of isoflurane diminished dorsal root-evoked polysynaptic, but not monosynaptic excitatory postsynaptic currents. In contrast, isoflurane prolonged the decay phase of evoked and miniature gamma-aminobutyric acidA receptor-mediated inhibitory postsynaptic currents. This may be a possible mechanism for antinociception by isoflurane in the spinal cord.
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Authors
T. Kohno, A. Wakai,