Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9022188 | International Congress Series | 2005 | 14 Pages |
Abstract
The conjugate was shown to significantly increase the survival of mice compared to repeated injections of PBS or free ADR. These results demonstrate a marked improvement over existing chemotherapy strategies based on ADR alone. p97 may have significant potential as an effective vehicle for the delivery of therapeutic drugs across the BBB.
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Authors
Reinhard Gabathuler, G. Arthur, M. Kennard, Q. Chen, S. Tsai, J. Yang, W. Schoorl, T.Z. Vitalis, W.A. Jefferies,