Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9028800 | Chemico-Biological Interactions | 2005 | 12 Pages |
Abstract
Lysolipids were found to be more toxic for K562wt than for K562adr cells. LPS and LPC16 produced an increased of a mobile lipid NMR signal and amount of lipid droplets in K562wt cells only. LPC18, with the lowest toxicity, has shown more intense effects on NMR spectra with a large increase of lipid NMR signal without changes in lipid droplet staining. The functioning of the P-gp pump and membrane asymmetry were not modified by any of the lysolipids used.
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Authors
Mounir Traïkia, Carole Marbeuf-Gueye, Edith Hantz, Laurence Le Moyec,