Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9035008 | Toxicology | 2005 | 14 Pages |
Abstract
Both selective and non-selective COX-2 inhibitors were toxic for rats fetuses when administered in the highest dose. Unlike DFU, piroxicam was also highly toxic to the dams. Prenatal exposure to selective COX-2 inhibitors does not increase the risk of ventricular septal and midline defects in rat when compared to non-selective drugs and historic control.
Keywords
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Authors
Franciszek Burdan,