Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9035260 | Toxicology | 2005 | 11 Pages |
Abstract
Overall these data suggest that AFB1 non-competitively inhibits mouse brain AChE by blocking access of the substrate to the active site or by inducing a defective conformational change in the enzyme through non-covalent binding interacting with the AChE peripheral binding site, or through both mechanisms.
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Authors
Maria Francesca Cometa, Paola Lorenzini, Stefano Fortuna, Maria Teresa Volpe, Annarita Meneguz, Maura Palmery,