Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9038759 | Toxicology in Vitro | 2005 | 9 Pages |
Abstract
Quantitative structure-activity relationships (QSAR) were developed between EC50 values and various molecular descriptors. The results suggest the existence of different mechanisms of action for the two classes of compounds. The findings obtained for phenolic herbicides are consistent with a protonophoric uncoupling mechanism, whereas for phenoxy herbicides a non-specific mode of action at membrane level can be hypothesized.
Keywords
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Authors
E. Argese, C. Bettiol, D. Marchetto, S. De Vettori, A. Zambon, P. Miana, P.F. Ghetti,