Osteoporosis secundaria a tratamiento con glucocorticoides

Secondary osteoporosis is caused by another medical condition or by drugs. Glucocorticoid-induced osteoporosis (GIOP) is the second in frequency only after the osteoporosis that occurs after menopause and is the most common form of drug-induced osteoporosis. It is estimated that over 50% of chronic glucocorticoid users will develop bone loss leading to fracture. We use a case of GIOP to review areas of continued controversy, including the pathogenesis of GIOP, methods for diagnosis of GIOP, and an evidence-based approach for both GIOP prevention and treatment.