Article ID Journal Published Year Pages File Type
9103713 Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 2005 6 Pages PDF
Abstract
In summary, with the exception of pravastatin, statins act as coronary vasodilators. Simvastatin, cerivastatin and atorvastatin but not lovastatin induced vasodilation displayed endothelium dependent- and endothelium-independent components. The endothelium-dependent effect of statins was mediated by NO and PGI2, while the mechanism of smooth muscle cells-dependent component remains to be determined.
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