Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9103713 | Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) | 2005 | 6 Pages |
Abstract
In summary, with the exception of pravastatin, statins act as coronary vasodilators. Simvastatin, cerivastatin and atorvastatin but not lovastatin induced vasodilation displayed endothelium dependent- and endothelium-independent components. The endothelium-dependent effect of statins was mediated by NO and PGI2, while the mechanism of smooth muscle cells-dependent component remains to be determined.
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Authors
Barbara Lorkowska, Stefan Chlopicki,