Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9104927 | Bone | 2005 | 13 Pages |
Abstract
Our data seem to indicate that osteoblast-like cells may contain two different fractions of TRACP, one that is released by monocytes and subsequently endocytosed by osteoblast-like cells and a second endogenous fraction that is present in an inactive proform. We hypothesize that the capacity of osteoblast-like cells to endocytose TRACP is important for the removal of this enzyme during or following the bone resorptive activity of the osteoclast.
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Authors
S. Perez-Amodio, I.M.C. Vogels, T. Schoenmaker, D.C. Jansen, S.L. Alatalo, J.M. Halleen, W. Beertsen, V. Everts,