Article ID Journal Published Year Pages File Type
9111144 Cytokine 2005 5 Pages PDF
Abstract
The IL-6sR released during platelet activation and complexed to IL-6 could act on cell types such as endothelial cells that do not possess IL-6Rα through binding to gp130.Besides, since we could not find IL-6R on platelet membrane, the potentiating effect of IL-6 on platelet function could be explained through binding of IL-6sR/IL-6 complex to platelet membrane gp130.
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Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
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