Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9111144 | Cytokine | 2005 | 5 Pages |
Abstract
The IL-6sR released during platelet activation and complexed to IL-6 could act on cell types such as endothelial cells that do not possess IL-6Rα through binding to gp130.Besides, since we could not find IL-6R on platelet membrane, the potentiating effect of IL-6 on platelet function could be explained through binding of IL-6sR/IL-6 complex to platelet membrane gp130.
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Authors
Rosana F. Marta, Nora P. Goette, Paola R. Lev, Carlos D. Chazarreta, Carlos J. Pirola, Felisa C. Molinas,