| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9111942 | Diabetes Research and Clinical Practice | 2005 | 8 Pages |
Abstract
In conclusion, NOD mouse islets with insulitis accumulate [18F]FDG markedly more than islets without insulitis or BALB/c islets. However, the relatively small difference in the [18F]FDG intensity between healthy and diseased islets, combined with the limited resolution ability of the positron emission tomography (PET), probably prevent the use of [18F]FDG in PET studies aiming at in vivo documentation of onset and progression of insulitis and prediabetes in mouse and man.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Endocrinology
![An autoradiographic study of [18F]FDG uptake to islets of Langerhans in NOD mouse](/preview/png/9111942.png "First Page Preview: An autoradiographic study of [18F]FDG uptake to islets of Langerhans in NOD mouse")
Authors
Teemu Kalliokoski, Olli Simell, Merja Haaparanta, Tapio Viljanen, Olof Solin, Juhani Knuuti, Pirjo Nuutila,