Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9117822 | Metabolism | 2005 | 9 Pages |
Abstract
r-metHuLeptin therapy plays an important role in insulin sensitivity. In females, it plays an additional role in normalizing menstrual function. This is likely to occur both from increasing insulin sensitivity and from restoring LH pulsatility. The persistent hypoleptinemic state in these subjects did not inhibit pubertal development.
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Authors
Carla Musso, Elaine Cochran, Edward Javor, Janice Young, Alex M. DePaoli, Phillip Gorden,