| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9121438 | FEMS Microbiology Letters | 2005 | 6 Pages |
Abstract
Blocking peptidoglycan synthesis in Escherichia coli with moenomycin or vancomycin led to the accumulation of UDP-MurNAc-pentapeptide and of its immediate upstream precursors, whereas with cephaloridine or penicillin G the pool of UDP-MurNAc-pentapeptide decreased. With MraY and FtsW deficiencies the decrease of UDP-MurNAc-pentapeptide was accompanied by an increase of the upstream nucleotide precursors and the appearance of UDP-MurNAc-tetrapeptide.
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Authors
Beatriz Lara, Dominique Mengin-Lecreulx, Juan A. Ayala, Jean van Heijenoort,