| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9121647 | FEMS Microbiology Letters | 2005 | 7 Pages |
Abstract
Deinococcus radiodurans shows remarkable resistance to reactive oxygen species (ROS), generated by irradiation. Disruption of recX (dr1310) in D. radiodurans using targeted mutagenesis method enhanced its ROS scavenging activity, and recX overexpression in this bacterium repressed its antioxidant activity significantly. Further analyses on catalase and superoxide dismutase, two important antioxidant proteins in cells, showed that RecX could repress the induction of antioxidant enzymes, revealing that it negatively regulates the ROS scavenging activity in D. radiodurans.
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Authors
Duohong Sheng, Guanjun Gao, Bing Tian, Zhenjian Xu, Zhiguo Zheng, Yuejin Hua,