Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9139104 | Journal of Structural Biology | 2005 | 8 Pages |
Abstract
Automated data acquisition procedures have changed the perspectives of electron tomography (ET) in a profound manner. Elaborate data acquisition schemes with autotuning functions minimize exposure of the specimen to the electron beam and sophisticated image analysis routines retrieve a maximum of information from noisy data sets. 'TOM software toolbox' integrates established algorithms and new concepts tailored to the special needs of low dose ET. It provides a user-friendly unified platform for all processing steps: acquisition, alignment, reconstruction, and analysis. Designed as a collection of computational procedures it is a complete software solution within a highly flexible framework. TOM represents a new way of working with the electron microscope and can serve as the basis for future high-throughput applications.
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Authors
Stephan Nickell, Friedrich Förster, Alexandros Linaroudis, William Del Net, Florian Beck, Reiner Hegerl, Wolfgang Baumeister, Jürgen M. Plitzko,