Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9152266 | Respiratory Physiology & Neurobiology | 2005 | 10 Pages |
Abstract
To determine whether intense, prolonged activity can induce transient pulmonary edema, eight highly trained male cyclists (mean ± S.D.: age, 26.9 ± 3.0 years; height, 179.9 ± 5.7 cm; weight, 76.1 ± 6.5 kg) performed a 45-min endurance cycle test (ECT). VËO2,max was determined (4.84 ± 0.4 L minâ1, 63.7 ± 2.6  ml minâ1 gâ1) and the intensity of exercise for the ECT was set at 10% below ventilatory threshold (â¼76% VËO2,max 300 ± 25 W). Pre- and post-exercise pulmonary diffusion (DLCO) measurements and magnetic resonance imaging of the lung were made. DLCO and pulmonary capillary blood volume (VC) decreased 1 h post-exercise by 12% (P = 0.004) and 21% (P = 0.017), respectively, but no significant change in membrane diffusing capacity (DM) was found. The magnetic resonance scans demonstrated a 9.4% increase (P = 0.043) in pulmonary extravascular water 90 min post-exercise. These data support the theory that high intensity, sustained exercise in well-trained athletes can result in transient pulmonary edema.
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Authors
D.C. McKenzie, T.J. O'Hare, J. Mayo,