Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9152495 | Respiratory Physiology & Neurobiology | 2005 | 10 Pages |
Abstract
The study objectives were to compare in vitro transportability and physical properties of respiratory mucus, obtained invasively by direct collection (DC) right after endotracheal intubation and non-invasively by sputum induction with 3% hypertonic saline solution inhalation (SI) 24 h before the anesthesia. Twenty-two patients with no pulmonary disease scheduled for elective abdominal surgical procedures were studied. The parameters analyzed and the main results are as follows. (1) Transportability by cilia (MCT), SI was higher than DC (0.94 ± 0.25 and 0.62 ± 0.25; P < 0.001). There was a significant correlation between the two methods and DC could be estimated by: DC = 0.21 + (0.44 SI) (r = 0.44; P < 0.001). (2) Transportability by cough (CC), SI was higher than DC (68.23 ± 32.1 and 33.58 ± 19.04 mm; P = 0.002). (3) Contact angle (CA), SI was lower than DC (10 ± 3° and 22 ± 14°; P = 0.025). (4) Rheological properties (no significant difference obtained between SI and DC). These results indicated that SI changes mucus physical properties and transportability in non-expectorators.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Physiology
Authors
Claudia S. Albertini-Yagi, Regiani C. Oliveira, Joaquim E. Vieira, Elnara M. Negri, Luciana R. de Oliveira, Paulo H.N. Saldiva, Geraldo Lorenzi-Filho,