| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9157685 | Atherosclerosis | 2005 | 11 Pages |
Abstract
Inhibition of intestinal cholesterol absorption by phytosterols is not mediated via transcriptional changes in ABCA1, ABCG5, ABCG8 or NPC1L1. Changes suggestive of immunomodulation are associated with the hypocholesterolemic effect of phytosterols and with apoE deficiency.
Keywords
serum amyloid A3NPC1L1LXRVLDLIDLABCG5SREBPLFCFDPsNCEPMARCOABCA1ALTRT-PCRABCG8Foxq1HDLLDL receptor-deficient miceETV6FPLCSAA3ApoE−/−ATP-binding cassette transporter A1GC–MShigh-density lipoproteinLDLR−/−AtherosclerosisAlanine aminotransferaseApoeapolipoprotein ENational Cholesterol Education ProgramATP-binding cassette transporterImmune systemregCancerfast protein liquid chromatographyfarnesyl diphosphate synthasePhytosterolsvery-low-density lipoproteinIntermediate-density lipoprotein Low-density lipoproteinLDLApoE-deficient miceReverse-transcriptase polymerase chain reactionsterol regulatory element binding proteinliver X receptorcholesterolmacrophage receptor with collagenous structure
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Authors
Laura Calpe-Berdiel, Joan Carles Escolà -Gil, Vicent Ribas, Aleix Navarro-Sastre, Josep Garcés-Garcés, Francisco Blanco-Vaca,