Estudio mutacional del gen HSPA2 en pacientes estériles y en controles

The results from the present study suggest that the presence of pathogenic mutations in the HSPA2 gene, if any, should be a relatively uncommon cause of infertility in infertile patients. Of the polymorphisms detected, the change 684 C>T has been detected at a significantly increased allelic frequency, suggesting that this polymorphism may be as a risk factor for azoospermia. The possibility is now open to confirm these findings in subsequent studies using the oligonucleotides and conditions described in a larger group of patients and controls.