| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9160329 | Cardiovascular Pathology | 2005 | 8 Pages |
Abstract
The results indicate that matrix remodeling in calcific AS involves the expression and activation of MMPs. Activated leukocytes, by the secretion of TNFα, may stimulate valvular myofibroblasts to proliferate and express MMPs, thus regulating actively the matrix remodeling in calcific AS.
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Jens J. Kaden, Carl-Erik Dempfle, Rainer Grobholz, Carolin S. Fischer, Daniela C. Vocke, Refika Kılıç, Aslıhan Sarıkoç, Rafael Piñol, Siegfried Hagl, Siegfried Lang, Martina Brueckmann, Martin Borggrefe,