Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9161634 | Chest | 2005 | 7 Pages |
Abstract
PDE5 inhibition with sildenafil improves cardiac output by balanced pulmonary and systemic vasodilation, and augments and prolongs the hemodynamic effects of inhaled NO in patients with chronic congestive heart failure and PH.
Keywords
Type 5 PhosphodiesterasecGMP+dp/dtmaxPCWPPDE5SVRNYHANew York Heart AssociationRight ventricularLeft ventricularcardiac indexPVRVasodilator agentsHypertension, pulmonarypulmonary capillary wedge pressureSystemic vascular resistancePulmonary vascular resistancecyclic guanosine monophosphateHeart failure, congestiveNitric oxidePulmonary hypertension
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Authors
John J. MD, Anjli MD, Luca M. MD, G. William MD, Warren M. MD, Kenneth D. MD, Marc J. MD,